New South Pole Telescope shows Omaga = 1.006 +- 0.004
The South Pole Telescope published the new results.Omega_K=-0.003+0.014-0.018. Using the SPT+WMAP7 data, the spectral index of scalar fluctuations tis ns=0.9623+/-0.0097 in the LCDM model, a 3.9sigma preference for a scale-dependent spectrum with ns<1.
Dark Matter Filament Studied in 3-D for the First Time
Astronomers using the NASA/ESA Hubble Space Telescope have studied a giant filament of dark matter in 3D for the first time. Extending 60 million light-years from one of the most massive galaxy clusters known, the filament is part of the cosmic web that constitutes the large-scale structure of the Universe, and is a leftover of the very first moments after the Big Bang. If the high mass measured for
Newborn cortical neurons: only for neonates?
Despite a century of debate over the existence of adult cortical neurogenesis, a consensus has not yet been reached. Here, we review evidence of the existence, origin, migration, and integration of neurons into the adult and neonatal cerebral cortex. We find that the lack of consensus likely stems from the low rate of postnatal cortical neurogenesis that has been observed, the fact that neurogenesis
Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging
Genetically encoded calcium indicators (GECIs) are powerful tools for systems neuroscience. Recent efforts in protein engineering have significantly increased the performance of GECIs. The state-of-the art single-wavelength GECI, GCaMP3, has been deployed in a number of model organisms and can reliably detect three or more action potentials in short bursts in several systems in vivo. Akerboom
Genetically encoded optical indicators for the analysis of neuronal circuits
In a departure from previous top-down or bottom-up strategies used to understand neuronal circuits, many forward-looking research programs now place the circuit itself at their centre. This has led to an emphasis on the dissection and elucidation of neuronal circuit elements and mechanisms, and on studies that ask how these circuits generate behavioural outputs. This movement towards circuit-centric
In vivo genome editing using a high-efficiency TALEN system
Improvements in artificial transcription activator-like effector nucleases (TALENs) provide a powerful new approach for targeted zebrafish genome editing and functional genomic applications1–5. Using the Goldy TALEN modified scaffold and zebrafish delivery system, it was shown that this enhanced TALEN toolkit has a high efficiency in inducing locus-specific DNA breaks in
ENCODE Project Writes Eulogy For Junk DNA
SCIENCE VOL 337 7 SEPTEMBER 201230 research papers, including six in Nature and additional papers published by Science, sound the death knell for the idea that our DNA is mostly littered with useless bases. A decadelong project, the Encyclopedia of DNA Elements (ENCODE), has found that 80% of the human genome serves some purpose, biochemically speaking.
Axion search by Liquid Xenon
Arisaka's group has studied a possibility of searching for axion and axion-like particles by liquid Xenon detectors such as XENON100 and XENON1T. The paper has been submitted to Astroparticle Physcis Journal, and available athttp://arxiv.org/abs/1209.3810
Disorder of Neuronal Circuits in Autism Is Reversible, New Study Suggests
People with autism suffer from a pervasive developmental disorder of the brain that becomes evident in early childhood. Peter Scheiffele and Kaspar Vogt, Professors at the Biozentrum of the University of Basel, have identified a specific dysfunction in neuronal circuits that is caused by autism. In the journal Science, the scientists also report about their success in reversing these neuronal changes.
Cross-sensory transfer of sensory-motor information: visuomotor learning affects performance on an audiomotor task, using sensory-substitution
Visual-to-auditory sensory-substitution devices allow users to perceive a visual image using sound. Using a motor-learning task, researchers in Israel found that new sensory-motor information was generalized across sensory modalities. They imposed a rotation when participants reached to visual targets, and found that not only seeing, but also hearing the location of targets via a sensory-substitution